Cytosolic proteins can exploit membrane localization to trigger functional assembly
نویسندگان
چکیده
منابع مشابه
Cytosolic proteins can exploit membrane localization to trigger functional assembly
Cell division, endocytosis, and viral budding would not function without the localization and assembly of protein complexes on membranes. What is poorly appreciated, however, is that by localizing to membranes, proteins search in a reduced space that effectively drives up concentration. Here we derive an accurate and practical analytical theory to quantify the significance of this dimensionalit...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2018
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1006031